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Boaz Barak Lab - Brain behavior lab
brain-system-works-neuron-receives-chemical-electrical-signals-background-generative-ai.jp

Exploring Myelination and Brain Development in Neurodevelopmental Disorders

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Selected Publications:

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Levy G, Rokach M, Fischer I, Kimchi-Feldhorn O, Shoob S, Bar E, Rosenberg T, Bartman J, Parnas H, Grad M, Israel-Elgali I, Sfadia E.G, Trangle S.S, Vainshtein A, Eshed-Eisenbach Y, Jahn O, Siems S.B, Werner H.B, Shomron N, Assaf Y, Peles E, Slutsky I, Marco A and Barak B.

2025

Boaz Barak Neuroscience, Tel Aviv University

Tackling myelin deficits in neurodevelopmental disorders using drug delivery systems 

Rokach M, Portioli C, Brahmachari S, Estevão BM, Decuzzi P and Barak B.

2024

Boaz Barak Neuroscience, Tel Aviv University

Shank3 mutation impairs glutamate signaling and myelination in ASD mouse model and human iPSC-derived OPCs

Fischer I, Shohat S, Leichtmann-Bardoogo Y, Nayak R, Wiener G, Rosh I, Shemen A, Tripathi U, Rokach M, Bar E, Hussein Y, Carolin Castro A, Chen G, Soffer A, Schokoroy-Trangle S, Elad-Sfadia G, Assaf Y, Schroeder A, Monteiro P, Stern S, Maoz B and Barak B.

2024

Boaz Barak Neuroscience, Tel Aviv University

Neuronal deletion of Gtf2i results in developmental microglial alterations in a mouse model related to Williams syndrome

Bar E, Fischer I, Rokach M, Elad-Sfadia G, Shirenova S, Ophir O, Schokoroy-Trangle S, Okun E, Barak B.

2024

Boaz Barak Neuroscience, Tel Aviv University

In individuals with Williams syndrome, dysregulation of methylation in non-coding regions of neuronal and oligodendrocyte DNA is associated with pathology and cortical development 

Schokoroy Trangle S, Rosenberg T, Parnas H, Levy G, Bar E, Marco A and Barak B. 

2022

Boaz Barak Neuroscience, Tel Aviv University

Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug 

Barak B , Zhang Z, Liu Y, Nir A, Trangle S, Ennis  M, Levandowski K.M, Wang D, Quast K, L. Boulting G.L, Li Y, Bayarsaihan D, He Z  and Feng  G. 

2019

Boaz Barak Neuroscience, Tel Aviv University

Selected News:

Selected Talk:

Beyond neurons: A paradigm shift in autism research

Beyond neurons_ A paradigm shift in autism research
Boaz Barak lab team members

The Lab Team:

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Research funds are limited, especially for rare diseases, while costs continue to rise. 

 

Every amount makes a difference!

Every donation helps and brings us one step closer to improve the understanding and treatment of Williams syndrome and autism spectrum disorders (ASD).​​​

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